- Patent Title: Tricyclic heterocycle compounds useful as HIV integrase inhibitors
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Application No.: US17057875Application Date: 2019-05-31
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Publication No.: US11884683B2Publication Date: 2024-01-30
- Inventor: Tao Yu , Alan Whitehead , Yili Chen , Chunrui Sun , Zhiyong Hu , Kake Zhao , Ronald M. Kim , John A. McCauley
- Applicant: Merck Sharp & Dohme LLC , Tao Yu , Alan Whitehead , Yili Chen , Chunrui Sun , Zhiyong Hu , Kake Zhao , Ronald M. Kim , John A. McCauley
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme LLC
- Current Assignee: Merck Sharp & Dohme LLC
- Current Assignee Address: US NJ Rahway
- Agent Eric Greenwald; John C. Todaro
- International Application: PCT/US2019/034783 2019.05.31
- International Announcement: WO2019/236396A 2019.12.12
- Date entered country: 2020-11-23
- Main IPC: C07D498/22
- IPC: C07D498/22 ; C07D471/16 ; C07D491/22 ; A61P31/18 ; A61K45/06

Abstract:
The present invention relates to Tricyclic Heterocycle Compounds of Formula (I): (I) and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, R3, R4, R5, R6 and n are as defined herein. The present invention also relates to compositions comprising at least one Tricyclic Heterocycle Compound, and methods of using the Tricyclic Heterocycle Compounds for treating or preventing HIV infection in a subject.
Public/Granted literature
- US20210309671A1 TRICYCLIC HETEROCYCLE COMPOUNDS USEFUL AS HIV INTEGRASE INHIBITORS Public/Granted day:2021-10-07
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