Various embodiments of the present disclosure include a C-arm registration system employing a controller (70) for registering a C-arm (60) to an X-ray ripple marker (20) including a ripple pattern (50) radially extending from a fixed point (40) of the X-ray ripple marker (20). In operation, the controller (70) identifies the ripple pattern (50) within an X-ray image generated from an X-ray projection by the C-arm (60) and illustrative of a portion or an entirety of the ripple pattern (50), the identification of the ripple pattern (50) within the X-ray image is characteristic of a pose of the X-ray projection by the C-arm (60) relative to the X-ray rippler marker (20). The controller (70) further analyzes the ripple pattern (50) within the X-ray image to derive one or more transformation parameters definitive of the pose of the X-ray projection by the C-arm (60) relative to the X-ray rippler marker (20), and registers the C-arm (60) to the X-ray ripple marker (20) based on the transformation parameter(s).