A tool head with an anti-slip structure includes a combination segment formed on one side of the tool head, a driving segment formed on another side of the tool head, a groove segment formed the tool head and positioned between the combination segment and driving segment, and an anti-slip structure configured on the tool head and positioned between the groove segment and driving segment. With the anti-slip structure of a high friction coefficient and the groove segment, the friction can be increased so as to allow users to easily and quickly draw the tool head out of the hole of a removal tool.