发明授权
- 专利标题: T cells with reduced surface fucosylation and methods of making and using the same
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申请号: US16616928申请日: 2018-06-05
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公开(公告)号: US11891644B2公开(公告)日: 2024-02-06
- 发明人: Nicole Okeley , Jessica Field , Shyra Gardai , Ryan Heiser
- 申请人: Seagen Inc.
- 申请人地址: US WA Bothell
- 专利权人: Seagen Inc.
- 当前专利权人: Seagen Inc.
- 当前专利权人地址: US WA Bothell
- 代理机构: MORRISON & FOERSTER LLP
- 国际申请: PCT/US2018/036067 2018.06.05
- 国际公布: WO2018/226701A 2018.12.13
- 进入国家日期: 2019-11-25
- 主分类号: C12P21/00
- IPC分类号: C12P21/00 ; A61P35/02 ; A61K31/7024 ; A61K35/17 ; C12N5/0783 ; A61K31/70
摘要:
Methods of producing T cells having reduced surface fucosylation and use thereof in adoptive cell therapy, in particular, in cancer treatment are provided.
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