A modular multi-hinge retractable rigid-flexible coupling space manipulator based on origami structure includes a plurality of folding units and a manipulator base. The modular design idea is adopted for the manipulator, which is formed by combining multiple folding units. the driving motors installed on each folding unit drive the folding units to stretch out, draw back and fold over, so that the manipulator can stretch out and draw back flexibly and bend in any direction to complete the work tasks in a variety of complex environments. For the manipulator, the flexible materials are added to the links of the folding units, and deformation can be effectively compensated, the mechanism is simplified, and impact is relieved. The torsional spring is additionally arranged in the folding units to play a supporting role, so that the manipulator can be placed in forward or in inverted direction to match with various bases. The angle sensor is fixedly connected to the rotating pair formed by the chassis and the folding unit, and the rotating speed of the manipulator is monitored to avoid large impact or damage.