In an aspect, a satellite-based non-terrestrial network configures multiple preconfigured uplink resources (PURs) for a user equipment (UE). The PURs may be configured one PUR per beam, one PUR per cell, or one PUR for multiple cells. A serving cell of the UE and one or more cells adjacent to the serving cell may each have an associated PUR. The UE selects one of the multiple PURs and sends a transmission using the selected PUR without the UE have a connection to the network. The network sends an ACK in response to the transmission. Either the UE or the network can specify that the UE is to transmit using a first PUR and receive the ACK on a second PUR. The UE can specify when and which PUR to use in the transmission and the network can specify when and which PUR to use in the ACK.