Invention Grant
- Patent Title: Phenyl alkyl carbamate compounds for use in preventing or treating neurodegenerative disease
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Application No.: US17461695Application Date: 2021-08-30
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Publication No.: US11931332B2Publication Date: 2024-03-19
- Inventor: Yong Moon Choi
- Applicant: Bio-Pharm Solutions Co., Ltd.
- Applicant Address: KR Gyeonggi-do
- Assignee: Bio-Pharm Solutions Co., Ltd.
- Current Assignee: Bio-Pharm Solutions Co., Ltd.
- Current Assignee Address: KR Gyeonggi-do
- Agency: MORRISON & FOERSTER LLP
- Main IPC: A61K31/27
- IPC: A61K31/27 ; A61P25/16 ; A61P25/28

Abstract:
The present invention relates to a phenyl alkyl carbamate compound for use in preventing or treating neurodegenerative diseases. The phenyl alkyl carbamate compound of the present invention, prevented dopaminergic neuron loss, attenuated activation of astrocyte/microglia, repressed phosphorylated alpha-synuclein, and regulated phosphorylation levels of tau and acetylation levels of alpha-tubulin in the Parkinson's disease animal model. In addition, the phenyl alkyl carbamate compound of the present invention reduced the Amyloid-beta precursor protein and Amyloid-beta. Therefore, the phenyl alkyl carbamate compound of the present invention may be effectively used for preventing or treating neurodegenerative diseases.
Public/Granted literature
- US20220062220A1 PHENYL ALKYL CARBAMATE COMPOUNDS FOR USE IN PREVENTING OR TREATING NEURODEGENERATIVE DISEASE Public/Granted day:2022-03-03
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