- 专利标题： B7-H4 antibodies and methods and use thereof
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申请号： US17006670申请日： 2020-08-28
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公开(公告)号： US11939383B2公开(公告)日： 2024-03-26
- 发明人: Charles Kaplan , Alessandro Palumbo , Kathy Miller , Hangil Park , Nerissa Mendoza , Majid Ghoddusi
- 申请人： Five Prime Therapeutics, Inc.
- 申请人地址： US CA South San Francisco
- 专利权人： FIVE PRIME THERAPEUTICS, INC.
- 当前专利权人： FIVE PRIME THERAPEUTICS, INC.
- 当前专利权人地址： US CA South San Francisco
- 代理机构： MARSHALL, GERSTEIN & BORUN LLP
- 主分类号： C07K16/18
- IPC分类号： C07K16/18 ; A61K39/00 ; A61K39/395 ; A61P35/00 ; C07K16/28 ; G01N33/574
摘要：
The present disclosure provides antibodies and antigen-binding fragments thereof that specifically bind to human B7-H4. The anti-B7-H4 antibodies or antigen-binding fragments thereof are useful, for example in detecting B7-H4. Immunohistochemistry (IHC) can be used to detect B7-H4. The present disclosure also provides methods for treating cancer wherein increased B7-H4 has been detected, by administering a therapeutic anti-B7-H4 antibody or antigen-binding fragment thereof.
公开/授权文献
- US20210079096A1 B7-H4 ANTIBODIES AND METHODS AND USE THEREOF 公开/授权日：2021-03-18
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