The disclosure provides a method and a device used in a node for wireless communication. A first node first transmits a first sequence and a first radio signal, at least one of the first sequence or the first radio signal carrying a target identifier, then monitors a first type of information in a first time window, and finally transmits a second sequence and a second radio signal when no feedback is detected for the first sequence and the first radio signal in the first time window; wherein at least one of the second sequence or the second radio signal carries the target identifier. Through the above design, the disclosure realizes re-transmissions of a preamble and information included in a Message A in 2-step random access scenarios, thereby improving the spectrum efficiency and improving the performance of transmission of the Message A in 2-step random access scenarios.