- 专利标题： Anti-CD40 antibodies and uses thereof
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申请号： US17694890申请日： 2022-03-15
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公开(公告)号： US11952427B2公开(公告)日： 2024-04-09
- 发明人: Bryan C. Barnhart , Brigitte Devaux , Aaron P. Yamniuk , Shannon L. Okada , Brenda L. Stevens , James William West
- 申请人： Bristol-Myers Squibb Company , CytomX Therapeutics, Inc.
- 申请人地址： US NJ Princeton
- 专利权人： Bristol-Myers Squibb Company,CytomX Therapeutics, Inc.
- 当前专利权人： Bristol-Myers Squibb Company,CytomX Therapeutics, Inc.
- 当前专利权人地址： US NJ Princeton; US CA South San Francisco
- 代理机构： Sterne, Kessler, Goldstein & Fox P.L.L.C.
- 代理商 Daniel K. H. Choo
- 分案原申请号： US16958563
- 主分类号： C07K16/28
- IPC分类号： C07K16/28 ; C12N15/63
摘要：
Provided herein are agonistic antibodies, or antigen binding portions thereof, that bind to human CD40 and comprise improved heavy and light chain variable regions that impart improved yield and reduced aggregation. The invention also provides methods of treatment of cancer or chronic infection by administering the antibodies of the invention to a subject in need thereof.
公开/授权文献
- US20220324989A1 ANTI-CD40 ANTIBODIES AND USES THEREOF 公开/授权日：2022-10-13
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