An integrated circuit comprises a signal transmitter and a sampling circuit coupled to the signal transmitter, wherein the sampling circuit is to sample output voltage levels of an output of the signal transmitter at different respective times. The integrated circuit further comprises a measurement circuit coupled to the sampling circuit, wherein the measurement circuit is to compare the output voltage levels of the output of the signal transmitter to corresponding reference voltages to identify a first time when a first output voltage level equals a first reference voltage and a second time when a second output voltage level equals a second reference voltage. A time difference between the first time and the second time is used to configure a slew rate adjustment control of the signal transmitter.