Invention Grant
- Patent Title: Inhibitors of histone deacetylase useful for the treatment or prevention of HIV infection
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Application No.: US17438479Application Date: 2020-03-16
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Publication No.: US11976069B2Publication Date: 2024-05-07
- Inventor: Wensheng Yu , Joseph A. Kozlowski , Dane James Clausen , Jian Liu , James Fells
- Applicant: Merck Sharp & Dohme LLC
- Applicant Address: US NJ Rahway
- Assignee: Merck Sharp & Dohme LLC
- Current Assignee: Merck Sharp & Dohme LLC
- Current Assignee Address: US NJ Rahway
- Agent Eric Greenwald; John C. Todaro
- International Application: PCT/US2020/022882 2020.03.16
- International Announcement: WO2020/190827A 2020.09.24
- Date entered country: 2021-09-13
- Main IPC: C07D471/22
- IPC: C07D471/22 ; A61K31/426 ; A61K31/438 ; A61K31/4418 ; A61K31/4439 ; A61K31/4748 ; A61K31/505 ; A61K31/506 ; A61K31/513 ; A61K31/52 ; A61K31/635 ; A61K31/685 ; A61P31/18 ; C07D487/08 ; C07D491/18 ; C07D498/22
Abstract:
The present invention relates to Compounds of Formula I and Ia and pharmaceutically acceptable salts or prodrug thereof, wherein R1, R2, X, A and B are as defined herein. The present invention also relates to compositions comprising at least one compound of Formula I or Ia, and methods of using the compounds of Formula I or Ia for treating or preventing HIV infection in a subject.
Public/Granted literature
- US20220144837A1 INHIBITORS OF HISTONE DEACETYLASE USEFUL FOR THE TREATMENT OR PREVENTION OF HIV INFECTION Public/Granted day:2022-05-12
Information query
