Graphical user interface (GUI) based systems and methods are disclosed for regionizing full-size process plant displays for rendering on mobile user interface devices. A regionizer application receives a full-size process plant display that graphically represents at least a portion of a process plant that includes graphic representations of a plurality of process plant entities. The regionizer app determines display region(s) of the full-size process plant display that define corresponding view portions of the full-size process plant display. The display regions are transmitted to a mobile user interface device for rendering by a mobile display navigation app. The GUI based systems and methods can also automatically detect graphical process control loop display portions within full-size process plant displays for rendering on mobile user interface devices. The GUI based systems and methods can further refactor full-size process plant displays at various zoom and detail levels for visualization on mobile user interface devices.