A biocybernetics based system for detecting the biofeedback of human central nervous system activity and its optimization includes a non-invasive human brain interface device for the stimulation of the human brain using weak pulsed electromagnetic fields, a multi-sensor detection unit for the real-time measurement of various states of the central and autonomic nervous system, linked to a processing and feedback software supported by a database. Optimization processes are based on bio-cybernetic regulation, controlled by intrinsic feedback loops, generating measurable output for optimizing brain stimulation parameters as well as sensing feedback output to the human subject, in the form of visual, auditory, tactile, and highly immersive content related output including simulations in virtual and augmented reality.