Systems and methods for processing virtual machine I/O requests by virtualization extension modules. An example method comprises receiving, by a virtual machine monitor (VMM) mining on a host computer system, a request initiated by a virtual machine managed by the VMM; processing the request by a VMM extension module identified by one or more parameters of the request; invoking, by the VMM extension module, an application programming interface (API) exported by the VMM to perform an action identified by the request; and resuming execution of the virtual machine.