A display substrate and a display device are provided. Sub-pixels in a display substrate are divided into sub-pixel groups, wherein the sub-pixel groups include at least two sub-pixels, and at least two sub-pixels share the same pixel driving circuit; at least two light-emitting control sub-circuit in the pixel driving circuit correspond to at least two light-emitting element included in at least two sub-pixels, at least two light-emitting control sub-circuits correspond to at least two light-emitting control signal lines, and each light-emitting control sub-circuit is coupled to an output terminal of a compensation driving sub-circuit, a corresponding light-emitting element and a corresponding light-emitting control signal line; each light-emitting control sub-circuit is configured to control turning on or off a connection between the output terminal of the compensation driving sub-circuit and the corresponding light-emitting element under the control of the corresponding light-emitting control signal line.