Invention Grant
- Patent Title: Anti-BCMA antibody-drug conjugates and methods of use
-
Application No.: US17339549Application Date: 2021-06-04
-
Publication No.: US12043670B2Publication Date: 2024-07-23
- Inventor: Ryan Henry , Thiwanka Samarakoon , Nathan Fishkin , Ping Zhu , Ermira Pazolli , James Palacino , Juan C. Almagro
- Applicant: Eisai R&D Management Co., Ltd.
- Applicant Address: JP Tokyo
- Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee: Eisai R&D Management Co., Ltd.
- Current Assignee Address: JP Tokyo
- Agency: Finnegan, Henderson, Farabow, Garrett & Dunner, LLP
- Main IPC: C07K16/28
- IPC: C07K16/28 ; A61K39/00 ; A61K39/395 ; A61K45/06 ; A61K47/60 ; A61K47/65 ; A61K47/68 ; A61P35/00

Abstract:
Antibodies, antigen-binding fragments, and conjugates (e.g., antibody-drug conjugates (ADCs) such as those comprising a splicing modulator) that bind to BCMA are disclosed. The disclosure further relates to methods and compositions for use in the treatment of cancer by administering a composition provided herein.
Public/Granted literature
- US20220081486A1 ANTI-BCMA ANTIBODY-DRUG CONJUGATES AND METHODS OF USE Public/Granted day:2022-03-17
Information query