Systems, devices, and methods are provided to provide serial monitoring for a patient. An ultrasound system is provided which may include subdividing a portion of the anatomy of a patient into a number of zones. Imaging data may be received by an imaging device. This imaging data may be used to generate a severity score for each zone based on imaging parameters within the imaging data. Changes in the severity score for each zone may be displayed over time, such that a medical professional may monitor each zone in a serial manner.