A load/store circuit performs a first lookup of a load virtual address in a virtually-indexed, virtually-tagged first-level data cache (VIVTFLDC) that misses and generates a fill request that causes translation of the load virtual address into a load physical address, receives a response that indicates the load physical address is in a non-cacheable memory region and is without data from the load physical address, allocates a VIVTFLDC data-less entry that includes an indication that the data-less entry is associated with a non-cacheable memory region, performs a second lookup of the load virtual address in the VIVTFLDC and determines the load virtual address hits on the data-less entry, determines from the hit data-less entry it is associated with a non-cacheable memory region, and generates a read request to read data from a processor bus at the load physical address rather than providing data from the hit data-less entry.