Invention Grant
- Patent Title: Pharmaceutical composition comprising PIBF protein as active ingredient for prevention or treatment of inflammatory disease
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Application No.: US17418684Application Date: 2019-12-24
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Publication No.: US12070487B2Publication Date: 2024-08-27
- Inventor: You Sook Cho , Jun Pyo Choi , In Jeoung Baek , Hyouk Soo Kwon , So Young Park
- Applicant: UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION , THE ASAN FOUNDATION
- Applicant Address: KR Ulsan
- Assignee: UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION,THE ASAN FOUNDATION
- Current Assignee: UNIVERSITY OF ULSAN FOUNDATION FOR INDUSTRY COOPERATION,THE ASAN FOUNDATION
- Current Assignee Address: KR Ulsan; KR Seoul
- Agency: Oblon, McClelland, Maier & Neustadt, L.L.P.
- Priority: KR 20180172897 2018.12.28
- International Application: PCT/KR2019/018394 2019.12.24
- International Announcement: WO2020/138912A 2020.07.02
- Date entered country: 2021-06-25
- Main IPC: A61K38/17
- IPC: A61K38/17 ; A61K45/06 ; A61P11/06

Abstract:
The present invention relates to a pharmaceutical composition comprising a progesterone-induced blocking factor (PIBF) protein as an active ingredient for prevention or treatment of inflammatory disease. In the present invention, menopausal asthma animal models have been experimentally identified to decrease airway inflammation when treated with PIBF protein. Thus, the composition can be advantageously used in postmenopausal female asthma patients.
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