A temperature control system and a driving method thereof, and a liquid crystal apparatus are provided. In the temperature control system, an input voltage adjustment circuit is respectively coupled to a control signal output end of a control circuit, a power signal output end, and an input end of a signal amplification circuit, and is configured to control the signal strength of a basic electrical signal transmitted to the input end of the signal amplification circuit under the control of a control signal output from the control signal output end; the signal amplification circuit is configured to output a corresponding target electrical signal to a heating element according to the basic electrical signal, and the heating element is configured to adjust the heating temperature according to the target electrical signal; a temperature sensing circuit is respectively coupled to the heating element and the control circuit, and is configured to convert a sensed sensing signal into a feedback signal and transmit the feedback signal to the control circuit; and the control circuit is configured to control the control signal output from the control signal output end according to the received feedback signal.