- 专利标题： Diarylpyrazole compound, composition comprising same, and use thereof
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申请号： US17259472申请日： 2019-07-09
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公开(公告)号： US12076320B2公开(公告)日： 2024-09-03
- 发明人: Yihan Wang , Zhiqiang Liu
- 申请人： Shenzhen TargetRx, Inc.
- 申请人地址： CN Guangdong
- 专利权人： Shenzhen TargetRx, Inc.
- 当前专利权人： Shenzhen TargetRx, Inc.
- 当前专利权人地址： CN Guangdong
- 代理机构： Wolf, Greenfield & Sacks, P.C.
- 优先权： CN 1810764742.X 2018.07.12
- 国际申请： PCT/CN2019/095169 2019.07.09
- 国际公布： WO2020/011141A 2020.01.16
- 进入国家日期： 2021-01-11
- 主分类号： A61K31/506
- IPC分类号： A61K31/506 ; A61K45/06 ; A61P35/00 ; C07D403/04
摘要：
The present invention provides a diarylpyrazole compound, a composition comprising same, and a use thereof. The diarylpyrazole compound refers to the compound represented by a formula (I) or a tautomer, a stereoisomer, a prodrug, a crystalline form, a pharmaceutically acceptable salt thereof, a hydrate, or a solvent compound. The compound and the composition of the present invention can be used for treating BRAF kinase mutant proliferative diseases and have better pharmacokinetic properties.
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