Invention Grant
- Patent Title: Claudin-targeting agents and uses thereof
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Application No.: US17073817Application Date: 2020-10-19
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Publication No.: US12077565B2Publication Date: 2024-09-03
- Inventor: Enrique Gamero-Estevez , Aimee Ryan , Makoto Nagano
- Applicant: Enrique Gamero-Estevez , Aimee Ryan , Makoto Nagano
- Applicant Address: CA Montreal
- Assignee: Enrique Gamero-Estevez,Aimee Ryan,Makoto Nagano
- Current Assignee: Enrique Gamero-Estevez,Aimee Ryan,Makoto Nagano
- Current Assignee Address: CA Montreal
- Agency: BCF LLP
- Main IPC: C07K14/33
- IPC: C07K14/33

Abstract:
There are provided polypeptide constructs targeting claudin proteins that are useful for transiently disrupting tight junctions in a tissue. Pharmaceutical compositions and uses thereof in methods for enhancing delivery of therapeutic agents, for stem cell transplantation, and for treatment of male infertility are also provided.
Public/Granted literature
- US20210130418A1 CLAUDIN-TARGETING AGENTS AND USES THEREOF Public/Granted day:2021-05-06
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