Embedded sensors and onboard or off-board processing in an aligner case can detect aligner material and/or quality. Material detection can be used for counterfeit detection, or to trigger material specific events. Quality detection can include detection of common aligner failures or defects. A case for a dental appliance may include a tray for supporting the dental appliance, a cover coupled to the tray, and at least one sensor to detect a deformation of the dental appliance. A case for a dental appliance may include a tray for housing the dental appliance, a cover coupled to the tray, and at least one sensor configured to detect a change in material of the dental appliance.