Embodiments of the present disclosure relate to a method, system, and computer program product for efficient execution of a decision tree. According to the method, respective target values of a plurality of attributes of a target entity are obtained. Representations of a plurality of leaf nodes of a decision tree are obtained. Each of the representations indicates respective statistic values of a plurality of attributes of historical entities and a statistic prediction result determined from historical prediction results output at a respective one of the plurality of leaf nodes for the historical entities. Distance measures between the target entity and the plurality of leaf nodes are determined based on the target values and the statistic values indicated by the representations of the plurality of leaf nodes. A target prediction result for the target entity is determined based on the distance measures and the statistic prediction results of the historical entities.