A method for x-ray photon-counting data correction. The method includes generating, by a training data generation module, training input spectral projection data based, at least in part, on a reference spectral projection data. The training input spectral projection data includes at least one of a pulse pileup distortion, a charge splitting distortion, and/or noise. The method further includes training, by a training module, a data correction artificial neural network (ANN) based, at least in part, on training data. The data correction ANN includes a pulse pileup correction ANN, and a charge splitting correction ANN. The training data includes the training input spectral projection data and the reference spectral projection data.