Systems and methods for controlling industrial process automation and control systems can automatically, through the use of machine learning (ML) models and algorithms, extract plant assets from engineering diagrams and other plant engineering data sources. The systems and methods can establish asset relationships to create a plant asset registry and build an asset hierarchy from the plant assets. The systems and methods can generate an ontological knowledge base from the plant asset hierarchy, and provide an HMI for controlling the industrial process based on the plant asset hierarchy and the ontological knowledge base.