A film for manufacturing a pouch includes a contact layer including (A) a copolymer of ethylene and α-olefin having a density in the range of 0.870 g/cm3 to 0.910 g/cm3, alone or in mixture with (B) a polyolefin having a density in the range of 0.910 g/cm3 to 0.940 g/cm3, the contact layer including less than 0.10 wt %, preferably less than 0.07 wt %, of additives able to release a degradation compound further to gamma irradiation in the range of 25 kGy-50 kGy that can slow down or delay cellular growth. The process for manufacturing such a film, as well as the single-use pouch manufactured from that film are also described.