Invention Grant
- Patent Title: Quantitation of GLA proteins by mass spectrometric analysis
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Application No.: US17386234Application Date: 2021-07-27
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Publication No.: US12105093B2Publication Date: 2024-10-01
- Inventor: Bhagwat Prasad , Kenneth E. Thummel , Abdul Basit Shaikh , Allan E. Rettie
- Applicant: University of Washington , Washington State University
- Applicant Address: US WA Seattle
- Assignee: University of Washington,Washington State University
- Current Assignee: University of Washington,Washington State University
- Current Assignee Address: US WA Seattle; US WA Pullman
- Agency: Christensen O'Connor Johnson Kindness PLLC
- Main IPC: G01N33/68
- IPC: G01N33/68

Abstract:
Methods of LC-MS/MS quantification of γ-carboxylated proteins in plasma, serum, or blood, including dried blood spots, are disclosed. The methods can be used to determine patient-specific dosing of anticoagulant drugs and diagnosis of liver diseases, such as hepatocellular carcinoma.
Public/Granted literature
- US20220034901A1 QUANTITATION OF GLA PROTEINS BY MASS SPECTROMETRIC ANALYSIS Public/Granted day:2022-02-03
Information query
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