Methods, computer readable media, and devices for efficient application programming interface (API) processing with privacy protection include one method of receiving a user request for content from a client, parsing the user request for content to identify one or more request portions having a type of public information, customized information, and personal information, transmitting the one or more request portions to a corresponding microservice based on the type of the portion of content being requested, receiving one or more response portions, determining a type of the one or more portions of content, and in response to determining the type of a portion of content is not personal information, caching the portion of content based on the type of the portion of content, combining the one or more response portions into a user response, and sending the user response to the client.