发明授权
- 专利标题： Tetrahydrocurcumin compositions, methods of making, and methods of using the same
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申请号： US16811759申请日： 2020-03-06
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公开(公告)号： US12115138B2公开(公告)日： 2024-10-15
- 发明人: Donald Jeffrey Keyser , Alvaro F. Guillem , Bhupinder Singh , Richard A. Zager
- 申请人： RENIBUS THERAPEUTICS, INC.
- 申请人地址： US TX Southlake
- 专利权人： RENIBUS THERAPEUTICS, INC.
- 当前专利权人： RENIBUS THERAPEUTICS, INC.
- 当前专利权人地址： US TX Southlake
- 代理机构： Culhane PLLC
- 代理商 Jeff B. Vockrodt
- 主分类号： A61K31/12
- IPC分类号： A61K31/12 ; A61K9/127 ; A61K31/145 ; A61K31/16 ; A61K31/355 ; A61K31/375 ; A61K31/385 ; A61K31/7048 ; A61K47/10 ; A61K47/24 ; A61K47/34
摘要：
The present invention relates to novel tetrahydrocurcumin (THCu) compositions, novel methods of manufacturing, and methods of using these compositions for therapeutic applications. The novel synthetic pathway(s) result in THCu compositions that generally lack hexahydrocurcumin (HHC), and include an improved impurity profile with reduced additional species that are generally present in hydrogenated curcumin compositions.
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