A cranial drill guard operational for stabilizing a cranial drill bit, where the cranial drill guard includes: a proximal end with a proximal surface operational to receive the cranial drill bit; a distal end with a distal surface operational to interface with a skull bone, and a plurality of protruding ridges for attachment to the skull bone; a wall extending from the proximal end to the distal end; and a cavity within the wall, where the cavity extends longitudinally from the proximal end to the distal end and is operational to stabilize and guard the cranial drill bit. The wall may include one or more apertures that extend through the wall. Additional embodiments pertain to methods of perforating a skull bone of a cranium of a subject by utilizing the cranial drill guard.