An omnidirectional ghost imaging system based on a mechanism of bio-inspired retina-like includes a projection system, a collimating lens, a spectroscope, a curved mirror, a bucket detector, a data acquisition card and an arithmetic system. According to the application, the logarithmic polar mapping characteristic of the bio-inspired retina-like structure is utilized to generate an annular pattern sequence of the bio-inspired retina-like, and the pattern sequence is utilized to modulate a light source. After being reflected by the target around the curved mirror, the light is projected onto the curved mirror and diffusely reflected. According to the reversible characteristics of the optical path, the light after diffuse reflection is reflected to the original light source by the half mirror and half lens, and the reflected light intensity with target information is received by the bucket detector.