Embodiments of the disclosure relate to a display compensation system and a display panel compensation method. Specifically, it is possible to enhance the luminance uniformity of the display panel by generating a current temporary shift voltage by adding a unit offset voltage to a previous temporary shift voltage, generating modified image data by compensating for image data based on the current temporary shift voltage, driving the display panel based on the modified image data, and reducing the luminance difference value which is the difference between the maximum luminance data and the minimum luminance data for the display panel.