Real-time radio self-calibration may be provided. The self-calibration may begin by sampling a Transmission (TX) signal. An achievable Error Vector Magnitude (EVM) for one or more frames may be determined based on the TX signal. Link budgets for clients may be determined using a TX power and a supported Modulation and Coding Scheme (MCS). A per packet TX power is adjusted based on the achievable EVM and a TX retry rate. The PA linearity of the radio may also be adjusted based on the achievable EVM and the link budget. The client may be regrouped into a new MCS based on the link budget.