Provided are a parameter configuration and power determination method, device and a communication node. The parameter configuration method includes: configuring at least one transmission parameter setting set for a first communication node, where the transmission parameter setting set includes at least one first transmission parameter set, the first transmission parameter set includes at least one of: a transmission parameter set identifier for identifying the first transmission parameter set, target receiving power configuration information, path loss configuration information, or first indication information for indicating whether to reset a closed-loop power adjustment amount locally maintained by the first communication node. The problem of large overhead of the power control scheme in the NR multi-beam scenario in the existing art is solved, and achieving the effect of reducing the air interface signaling overhead.