Provided are an information processing device, a program, a trained model, a diagnostic support device, a learning device, and a prediction model generation method that can perform prediction with high accuracy using images. An information processing device includes: an information acquisition unit that receives an input of image data and non-image data related to a target matter; and a prediction unit that predicts an aspect related to the matter at a time different from a time when the image data is captured on the basis of the image data and the non-image data input through the information acquisition unit. The prediction unit performs weighting calculation by a calculation method, which outputs a combination of products of elements of a first feature amount calculated from the image data and a second feature amount calculated from the non-image data, to calculate a third feature amount in which the first feature amount and the second feature amount are fused and performs the prediction on the basis of the third feature amount.