Invention Grant
- Patent Title: Substituted indole and indazole compounds
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Application No.: US17287612Application Date: 2019-10-22
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Publication No.: US12172995B2Publication Date: 2024-12-24
- Inventor: John L. Gilmore , Shoshana L. Posy , Alaric J. Dyckman
- Applicant: BRISTOL-MYERS SQUIBB COMPANY
- Applicant Address: US NJ Princeton
- Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee: BRISTOL-MYERS SQUIBB COMPANY
- Current Assignee Address: US NJ Princeton
- Agent Gary Greenblatt
- International Application: PCT/US2019/057311 WO 20191022
- International Announcement: WO2020/086503 WO 20200430
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61K31/437 ; A61K31/4545 ; A61K31/5377 ; A61P37/00 ; C07D401/14 ; C07D491/107 ; C07D495/10 ; C07D519/00

Abstract:
Disclosed are compounds of Formula (I) N-oxides, or salts thereof, wherein X is CR1 or N; and G, A, R1; and n are defined herein. Also disclosed are methods of using such compounds as inhibitors of signaling through Toll-like receptor 7, or 8, or 9, and pharmaceutical compositions comprising such compounds. These compounds are useful in treating inflammatory and autoimmune diseases.
Public/Granted literature
- US20210403468A1 SUBSTITUTED INDOLE AND INDAZOLE COMPOUNDS Public/Granted day:2021-12-30
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