Invention Grant
![Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of FGFR tyrosine kinases](/docs/US/2024-12-31/US12180207B2/abs.jpg.600x600.jpg)
- Patent Title: Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of FGFR tyrosine kinases
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Application No.: US17416117Application Date: 2019-12-13
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Publication No.: US12180207B2Publication Date: 2024-12-31
- Inventor: James F. Blake , David A. Moreno , Li Ren , Tony P. Tang , Shane M. Walls
- Applicant: ARRAY BIOPHARMA INC.
- Applicant Address: US CO Boulder
- Assignee: ARRAY BIOPHARMA INC.
- Current Assignee: ARRAY BIOPHARMA INC.
- Current Assignee Address: US CO Boulder
- Agency: Meunier Carlin & Curfman LLC
- International Application: PCT/US2019/066278 WO 20191213
- International Announcement: WO2020/131627 WO 20200625
- Main IPC: C07D471/04
- IPC: C07D471/04 ; A61P35/00 ; C07D519/00
![Substituted pyrazolo[1,5-a]pyridine compounds as inhibitors of FGFR tyrosine kinases](/abs-image/US/2024/12/31/US12180207B2/abs.jpg.150x150.jpg)
Abstract:
Provided herein are compounds of the general Formula I: and stereoisomers and pharmaceutically acceptable salts or solvates thereof, in which Ring A, Ring B, Ring C, R1, R2, L, Y, and W have the meanings given in the specification, which are inhibitors of FGFR1, FGFR2, FGFR3 and/or FGFR4 and are useful in the treatment and prevention of diseases which can be treated with an FGFR inhibitor, including diseases or disorders mediated by FGFR1, FGFR2, FGFR3 and/or FGFR4.
Public/Granted literature
- US20220081438A1 SUBSTITUTED PYRAZOLO[1,5-A]PYRIDINE COMPOUNDS AS INHIBITORS OF FGFR TYROSINE KINASES Public/Granted day:2022-03-17
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