Systems and method of calibrating a range measurement system for a vehicle mounted on a guideway are disclosed. In some embodiments, a method includes: measuring a first time of transmission (TOT) between a first internal component of an on-board range measurement device and a second internal component of a wayside range measurement device. The first TOT is compared with a first pre-determined time. A health of the range measurement system is determined based on a difference between the first TOT and the first pre-determined time.