A method includes obtaining, using at least one image sensor of an electronic device, a first image frame and multiple second image frames of a scene. Each of the second image frames has an exposure time different from an exposure time of the first image frame. The method also includes generating, using at least one processor, blur kernels indicating a motion direction of the first image frame using an optical flow network. The method further includes refining, using the at least one processor, the blur kernels using a convolutional neural network. In addition, the method includes generating, using the at least one processor, a target image frame of the scene using the refined blur kernels and occlusion masks for the second image frames.