The present disclosure describes ultrasound imaging systems and methods configured to identify lung abnormalities by determining a uniformity characteristic of a region of interest within ultrasound image frames. Systems can include an ultrasound transducer configured to acquire echoes responsive to ultrasound pulses transmitted toward a pulmonary target region. A processor coupled with the transducer may be configured to generate an image frame from the acquired echoes and determine a uniformity characteristic of the region of interest below a pleural line in the image frame. The processor may also be configured to determine a presence or absence of a lung abnormality, e.g., lung consolidation, within the region of interest based on a value of the uniformity characteristic. If a lung abnormality has been determined to be present, the processor can generate an indicator of the same, which may be displayed on a user interface in communication with the processor.