Differential driving and/or differential sensing can reduce noise in the touch and/or display systems of a touch screen. In some examples, the touch sensor panel can include column and row electrodes routed vertically to a first edge of the touch sensor panel. In some examples, a touch sensor panel can be divided into banks. In some examples, the routing traces for rows can be implemented using four routing tracks per column for three banks. In some examples, the arrangement of routing traces within routing tracks can improve optical characteristics and/or reduce routing trace resistances and loading. In some examples, interconnections between routing traces and row electrodes can have a chevron pattern, an S-shape pattern, or a hybrid pattern. In some examples, differential sense routing can reduce cross-coupling within the touch sensor panel. In some examples, staggering differential drive signals can reduce parasitic signal loss.