Provided are a display substrate, a driving method thereof, and a display apparatus. The display substrate includes multiple sub-pixels, a sub-pixel includes a pixel drive circuit and a light emitting device, the pixel drive circuit includes an initial signal line (INIT), a reset signal line (Reset) and multiple transistors, the initial signal line includes a first branch (INIT-1). Multiple transistors include a drive transistor, a first reset transistor and a second reset transistor, the drive transistor provides a drive current to the light emitting device, the first reset transistor resets a gate of the drive transistor through the INIT-1 under control of the reset signal line. The second reset transistor resets a first terminal of the light emitting device through the INIT-1 under control of the reset signal line. The first reset transistor and the second reset transistor in a same sub-pixel are controlled by a same reset signal line.