A trained first model is generated through first learning using a first learning image group constituted of a normal image which is a medical image having no region of interest. An input image group including at least the medical image different from the first learning image group is input to the trained first model, and abnormality detection is performed. The extracted image used for learning to prevent erroneous recognition is sorted according to a result of the abnormality detection, and second learning using a second learning image group including at least the extracted image is performed. A second model that detects the region of interest is generated through the second learning.