A process for producing multi-layer game ball products includes the steps of extruding an inner layer precursor as a parison in a partial melt state, forming an outer layer, introducing the inner and outer layers into a mold and expanding the parison within the mold to form the multilayer game ball product. The outer layer may take the form of pre-cut panels vacuum supported in the mold and an intermediate layer may be provided for dimensional stability in the product. Subsequent to expanding the parison a filler such as foam may be injected into the center space for forming a core.