发明申请
US20020009449A1 Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
失效
使用CD2 / LFA-3相互作用的抑制剂预防或治疗抗原呈递细胞驱动的皮肤状况的方法
- 专利标题: Method of prophylaxis or treatment of antigen presenting cell driven skin conditions using inhibitors of the CD2/LFA-3 interaction
- 专利标题(中): 使用CD2 / LFA-3相互作用的抑制剂预防或治疗抗原呈递细胞驱动的皮肤状况的方法
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申请号: US09730465申请日: 2000-12-05
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公开(公告)号: US20020009449A1公开(公告)日: 2002-01-24
- 发明人: Barbara P. Wallner , Kevin D. Cooper
- 申请人: Biogen, Inc., a Massachusetts corporation
- 申请人地址: null
- 专利权人: Biogen, Inc., a Massachusetts corporation
- 当前专利权人: Biogen, Inc., a Massachusetts corporation
- 当前专利权人地址: null
- 主分类号: A61K039/395
- IPC分类号: A61K039/395
摘要:
Methods of using inhibitors of the CD2/LFA-3 interaction in treating skin conditions characterized by increased T cell activation and abnormal antigen presentation in the dermis and epidermis in mammals, including humans. Such conditions include psoriasis, UV damage, e.g., photoaging, atopic dermatitis, cutaneous T cell lymphoma such as mycosis fungoides, allergic and irritant contact dermatitis, lichen planus, alopecia areata, pyoderma gangrenosum, vitiligo, ocular cicatricial pemphigoid, and urticaria.
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