发明申请
- 专利标题： Process for preparing benzoxazin-4-one polymer conjugates
- 专利标题（中）： 制备苯并恶嗪-4-酮聚合物共轭物的方法
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申请号： US09891475申请日： 2001-06-26
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公开(公告)号： US20020028934A1公开(公告)日： 2002-03-07
- 发明人: Renae Dianna Fossum , Todd Laurence Underiner
- 主分类号： C07D265/26
- IPC分类号： C07D265/26 ; G01N033/53
摘要：
The present invention relates to a process for forming polymer conjugates which are useful as enzyme inhibitors. The process of the present invention comprises the steps of: a) reacting a polymer or copolymer alcohol to form a chloroformate; b) combining a substituted or unsubstituted anthranilic acid comprising an enzyme interaction attenuating unit; and a base catalyst wherein said base catalyst is a supported base catalyst, to form a substrate reactive admixture; and c) adding to said chloroformate formed in step (a) said substrate reactive admixture formed in step (b) to form a benzoxazin-4-one conjugate.
公开/授权文献
- US06504028B2 Process for preparing benzoxazin-4-one polymer conjugates 公开/授权日：2003-01-07
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