A remote keyless entry (RKE) transmitter includes voice activated control capability to allow the transmitter to receive key word inputs to control operation of multiple systems and devices. The use of voice recognition and key word commands allows the RKE transmitter to be operated nullhands-free.null In addition, the transmitter can be arranged to control a plurality of different devices on a vehicle, such as door locks, trunk, and horn, as well as other devices such as a garage door opener without requiring a larger housing to accommodate additional dedicated control buttons and circuitry.