Disclosed is a method for controlling uplink transmission power in a handover region by a UE in communication with a Node B using an FCS scheme. The UE stores TPC commands received for a specific duration from a plurality of cells in an active set, if the UE enters in the handover region during communication with a current best cell. If a next best cell is selected from the plurality of the cells, the UE determines a transmission power offset by comparing TPC commands from the current best cell with TPC commands from the next best cell for the specific duration at a time point where the best cell is changed from the current best cell to the next best cell. The UE transmits initial transmission power for the next best cell at a transmission power level determined considering the transmission power offset.